Aniston's biggest box office success to date was her appearance in the comedy Bruce Almighty (2003), in which she played the girlfriend of Jim Carrey's title character.  Aniston then starred in the romantic comedy film Along Came Polly (2004) opposite Ben Stiller.  Aniston appeared in two major studio films, the thriller Derailed (2005), and the rom-com Rumor Has It. . . (2005).  Aniston appeared in the low-budget drama Friends with Money (2006), which was first shown at the Sundance Film Festival and received a limited release.  Aniston's next film was the romantic comedy The Break-Up (2006) alongside Vince Vaughn which received mixed reviews. The A. V. Club's Keith Phipps gave the film a negative review stating, "It’s like watching the 'we were on a break' episode of Friends stretched to feature length, and without the blessed relief of commercial breaks or the promise of Seinfeld around the corner. "CinemaBlend gave the film a positive review stating, "In an era of formulaic romantic movies that bear no resemblance to reality, The Break-Up offers a refreshing flipside. " It was released on June 2 and grossed approximately US$39. 17 million during its opening weekend. The film was successful at the box office grossing US$204 million worldwide. 
Well, in a new interview with Marie Claire for their December issue, the actress explained why she finally decided to address it. Actually touching on her divorce from Brad Pitt , Jen shared:
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Let me start by saying that addressing gossip is something I have never done. I don’t like to give energy to the business of lies, but I wanted to participate in a larger conversation that has already begun and needs to continue. Since I’m not on social media, I decided to put my thoughts here in writing.